Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 1/20 | 0.35 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.35 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.34 |
| ▸ | TUBB | P07437 | 3/20 | 0.34 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.34 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.34 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.34 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.34 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.34 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.34 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.34 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.34 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.34 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.34 |
| ▸ | TUBB6 | Q9BUF5 | 3/20 | 0.34 |
| ▸ | TUBB2B | Q9BVA1 | 3/20 | 0.34 |
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.34 |
| ▸ | FYN | P06241 | 3/20 | 0.34 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7470694 | 0.85 | SQOR (0.40) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL7468941 | 0.85 | PDE4B (0.40) | PDE4BSQORPDE4APDE4CPDE4D | |
| SCHEMBL7467257 | 0.84 | TOP1 (0.41) | ADORA2ARELAKDM4EAHR | |
| SCHEMBL7462457 | 0.79 | AKR1C3 (0.46) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL9955938 | 0.79 | PTGS2 (0.36) | SQORPTGS1 | |
| SCHEMBL7466053 | 0.78 | TAAR1 (0.39) | ADORA2AKDM4EHPGD | |
| SCHEMBL7355495 | 0.78 | HPRT1 (0.38) | PDE4BSQORPDE4APDE4CPDE4D | |
| SCHEMBL9053075 | 0.77 | ABL1 (0.44) | FYNADORA2A | |
| SCHEMBL16719652 | 0.76 | TUBB4A (0.40) | PDGFRBPDGFRATUBB4ATUBBTUBA3C | |
| SCHEMBL7464716 | 0.75 | GCGR (0.38) | ADORA2AKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1244617-A1 | SUBSTITUTED AMINOALKYLAMIDE DERIVATIVES AS ANTAGONISTS OF FOLLICLE STIMULATING HORMONE | Ortho-McNeil Pharmaceutical, Inc. (US) | 2002-10-02 | — | — | EP | claimed |
| WO-2001047875-A1 | SUBSTITUTED AMINOALKYLAMIDE DERIVATIVES AS ANTAGONISTS OF FOLLICLE STIMULATING HORMONE | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2001-07-05 | — | — | WO | claimed |