Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | OXTR | P30559 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.33 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.33 |
| ▸ | KDM2B | Q8NHM5 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | GPR6 | P46095 | 1/20 | 0.32 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.32 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7397848 | 0.84 | GPR6 (0.33) | ALDH1A1GPR6GPR119HSD11B1 | |
| SCHEMBL3563776 | 0.80 | GRIK1 (0.43) | ALDH1A1KDM2BRAB9AGPR6PDE4A | |
| SCHEMBL7356519 | 0.80 | GPR119 (0.49) | ALDH1A1GPR119PDE4APDE4BPDE4C | |
| SCHEMBL3554378 | 0.79 | MEN1 (0.37) | ALDH1A1KDM2BRAB9AGPR6PDE4B | |
| SCHEMBL8094956 | 0.78 | LIPG (0.38) | GPR119HRH3 | |
| SCHEMBL9013863 | 0.73 | GPR119 (0.38) | GPR119HRH3 | |
| SCHEMBL7333820 | 0.73 | OXTR (0.41) | OXTRALDH1A1AVPR2AVPR1AACACB | |
| SCHEMBL7333661 | 0.72 | OXTR (0.42) | OXTRALDH1A1AVPR2AVPR1AACACB | |
| SCHEMBL8088578 | 0.72 | EPHX2 (0.40) | GPR119HRH3 | |
| SCHEMBL7335906 | 0.72 | OXTR (0.37) | OXTRGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0805681-A4 | TOCOLYTIC OXYTOCIN RECEPTOR ANTAGONISTS | MERCK & CO INC (US) | 1998-05-06 | — | — | EP | disclosed |
| EP-0805681-A1 | TOCOLYTIC OXYTOCIN RECEPTOR ANTAGONISTS | Merck & Co., Inc. (US) | 1997-11-12 | — | — | EP | disclosed |
| WO-1996022775-A1 | TOCOLYTIC OXYTOCIN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1996-08-01 | — | — | WO | disclosed |