Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8094956 | 0.78 | LIPG (0.38) | GPR119HRH3 | |
| SCHEMBL8088578 | 0.78 | EPHX2 (0.40) | GPR119HRH3 | |
| SCHEMBL8089444 | 0.78 | AR (0.46) | — | |
| SCHEMBL8092927 | 0.77 | EPHX2 (0.37) | HRH3 | |
| SCHEMBL8088615 | 0.75 | EPHX2 (0.36) | GPR119HRH3 | |
| SCHEMBL7342953 | 0.75 | OXTR (0.36) | GPR119 | |
| SCHEMBL7342824 | 0.73 | OXTR (0.40) | GPR119 | |
| SCHEMBL7356525 | 0.73 | HIF1A (0.34) | GPR119HRH3 | |
| SCHEMBL7333661 | 0.72 | OXTR (0.42) | GPR119SMN1; SMN2 | |
| SCHEMBL5209322 | 0.72 | CTSK (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5580883-A | INHIBITING DEGENERATION AND NECROCYTOSIS OF CEREBRAL NERVE CELLS CAUSED BY OXIDATIVE STRESS INDUCING GLUTAMIC ACID IN MAMMALS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-12-03 | — | — | US | disclosed |
| EP-0449195-A2 | Aminobenzene compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1991-10-02 | — | — | EP | disclosed |