Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 3/20 | 0.39 |
| ▸ | NOS3 | P29474 | 2/20 | 0.39 |
| ▸ | TTR | P02766 | 2/20 | 0.36 |
| ▸ | ALB | P02768 | 2/20 | 0.36 |
| ▸ | IDH1 | O75874 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 3/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5898263 | 0.84 | TTR (0.39) | NOS1NOS3TTRALBIDH1 | |
| SCHEMBL16958451 | 0.82 | NOS1 (0.40) | NOS1NOS3IDH1ALDH1A1CYP2A6 | |
| SCHEMBL27748133 | 0.81 | NOS1 (0.39) | NOS1NOS3TTRALBIDH1 | |
| SCHEMBL23536729 | 0.81 | TAAR1 (0.46) | NOS1NOS3ALDH1A1CYP2A6BACE1 | |
| SCHEMBL7358314 | 0.81 | NOS1 (0.39) | NOS1NOS3TTRALBIDH1 | |
| SCHEMBL7429249 | 0.79 | TDP1 (0.42) | IDH1ALDH1A1KDM4EALOX5GAA | |
| SCHEMBL6418650 | 0.79 | PGK1 (0.44) | ALDH1A1KDM4EALOX5GAAMAPT | |
| SCHEMBL22477339 | 0.78 | CYP2A6 (0.39) | NOS1NOS3TTRALBIDH1 | |
| SCHEMBL11982666 | 0.78 | CYP2A6 (0.50) | NOS1NOS3TTRALBIDH1 | |
| SCHEMBL7430324 | 0.77 | NOS3 (0.33) | NOS1NOS3TTRALBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3915998-B1 | APPLICATION OF SALIDROSIDE DERIVATIVE IN SKIN-WHITENING AGENT FOR EXTERNAL USE | SHANGHAI CHEERMORE BIOLOGICAL TECH CO LTD (CN) | 2023-01-18 | — | — | EP | disclosed |
| EP-1027332-A1 | NOVEL LACTAM METALLOPROTEASE INHIBITORS | Du Pont Pharmaceuticals Company (US) | 2000-08-16 | — | — | EP | disclosed |
| WO-1999018074-A1 | NOVEL LACTAM METALLOPROTEASE INHIBITORS | Britol-Myers Squibb Pharma Company (US) | 1999-04-15 | — | — | WO | disclosed |