Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.49 |
| ▸ | HTR3B | O95264 | 1/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.49 |
| ▸ | HTR3A | P46098 | 1/20 | 0.49 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.49 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.45 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.45 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.45 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7357427 | 0.82 | MAPT (0.41) | MAPTMAPK1TPSAB1TPSD1TPSG1 | |
| Hydrochloric Acid SCHEMBL7361272 | 0.81 | MAPT (0.53) | MAPTHTR3EHTR3BADRB1HTR3A | |
| SCHEMBL7366682 | 0.80 | ADRB1 (0.50) | MAPTHTR3EHTR3BADRB1HTR3A | |
| SCHEMBL12814351 | 0.79 | ITGB3 (0.62) | MAPTHTR3EHTR3BADRB1HTR3A | |
| SCHEMBL12814058 | 0.79 | NPSR1 (0.58) | MAPTHTR3EHTR3BADRB1HTR3A | |
| SCHEMBL14922265 | 0.78 | ADRB1 (0.57) | MAPTHTR3EHTR3BADRB1HTR3A | |
| Hydrochloric Acid SCHEMBL12814057 | 0.78 | NPSR1 (0.57) | MAPTHTR3EHTR3BADRB1HTR3A | |
| Hydrochloric Acid SCHEMBL7362069 | 0.77 | TPSAB1 (0.53) | MAPTMAPK1TPSAB1TPSD1TPSG1 | |
| Hydrochloric Acid SCHEMBL7369072 | 0.77 | TPSAB1 (0.53) | MAPTMAPK1TPSAB1TPSD1TPSG1 | |
| Trifluoroacetic Acid SCHEMBL7358937 | 0.77 | ATM (0.48) | MAPTHTR3EHTR3BADRB1HTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5994356-A | ANTICOAGULANT | KARL THOMAE (DE) | 1999-11-30 | — | — | US | disclosed |
| EP-0892783-A1 | CARBOXYLIC ACID DERIVATIVES WITH AN AGGREGATION-INHIBITING ACTION | Dr. Karl Thomae GmbH (DE) | 1999-01-27 | — | — | EP | disclosed |
| WO-1997037975-A1 | CARBOXYLIC ACID DERIVATIVES WITH AN AGGREGATION-INHIBITING ACTION | DR. KARL THOMAE GMBH (DE) | 1997-10-16 | — | — | WO | disclosed |