Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 16/20 | 0.62 |
| ▸ | MMP2 | P08253 | 11/20 | 0.62 |
| ▸ | MMP1 | P03956 | 7/20 | 0.62 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7365907 | 0.88 | MMP2 (0.48) | MMP13MMP2MMP1MMP9 | |
| Hydrochloric Acid SCHEMBL7751277 | 0.79 | MMP13 (0.62) | MMP13MMP2MMP1SMN1; SMN2 | |
| SCHEMBL6767563 | 0.76 | MMP13 (0.77) | MMP13MMP2MMP1 | |
| SCHEMBL6769491 | 0.76 | MMP13 (0.77) | MMP13MMP2MMP1 | |
| SCHEMBL6767568 | 0.76 | MMP13 (0.77) | MMP13MMP2MMP1 | |
| SCHEMBL7358585 | 0.74 | MMP13 (0.53) | MMP13MMP2MMP1MMP9HTT | |
| SCHEMBL7690204 | 0.73 | MMP13 (0.65) | MMP13MMP2MMP1MMP9 | |
| SCHEMBL7690202 | 0.73 | MMP13 (0.65) | MMP13MMP2MMP1MMP9 | |
| SCHEMBL7683904 | 0.73 | MMP13 (0.65) | MMP13MMP2MMP1MMP9 | |
| SCHEMBL7748825 | 0.72 | MMP13 (0.60) | MMP13MMP2MMP1MMP9SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235786-B1 | RHEUMATIC DISORDERS; BONE DISORDERS; ORAL DISEASES; ANTIULCER AGENTS; ANTITUMOR AGENTS | ABBOTT LABORATORIES | 2001-05-22 | — | — | US | claimed |
| WO-2000044712-A1 | N-HYDROXYFORMAMIDE DERIVATIVES AS INHIBITORS OF MATRIX METALLOPROTEINASES | ABBOTT LABORATORIES (US) | 2000-08-03 | — | — | WO | claimed |
| US-6235786-B1 | RHEUMATIC DISORDERS; BONE DISORDERS; ORAL DISEASES; ANTIULCER AGENTS; ANTITUMOR AGENTS | ABBOTT LABORATORIES | 2001-05-22 | — | — | US | disclosed |