Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.57 |
| ▸ | HTR3B | O95264 | 1/20 | 0.57 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.57 |
| ▸ | HTR3A | P46098 | 1/20 | 0.57 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.57 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.57 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.57 |
| ▸ | USP2 | O75604 | 3/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7354505 | 0.80 | ADRB2 (0.60) | HTR3EHTR3BADRB1HTR3AHTR3D | |
| SCHEMBL13724185 | 0.80 | MAPT (0.47) | HTR3EHTR3BADRB1HTR3AHTR3D | |
| SCHEMBL5597474 | 0.80 | KDM4E (0.46) | ADRB1LMNAHTR1AHTR7TSHR | |
| SCHEMBL5539647 | 0.78 | SIGMAR1 (0.45) | HTR3EHTR3BADRB1HTR3AHTR3D | |
| SCHEMBL29128246 | 0.78 | HTR3E (0.65) | HTR3EHTR3BADRB1HTR3AHTR3D | |
| SCHEMBL28956358 | 0.78 | NPC1 (0.47) | LMNAHTR1ALTA4HALDH1A1CYP2C19 | |
| SCHEMBL2107593 | 0.76 | ADRB1 (0.64) | HTR3EHTR3BADRB1HTR3AHTR3D | |
| Phenylpiperazine SCHEMBL24889 | 0.73 | ADRB1 (1.00) | HTR3EHTR3BADRB1HTR3AHTR3D | |
| Phenylpiperazine SCHEMBL55125 | 0.73 | ADRB1 (1.00) | HTR3EHTR3BADRB1HTR3AHTR3D | |
| Phenylpiperazine SCHEMBL29135595 | 0.73 | ADRB1 (1.00) | HTR3EHTR3BADRB1HTR3AHTR3D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101541331-A | Novel macrolides and ketolides with antimicrobial activity | WOCKHARDT RESEARCH CENTER (IN) | 2009-09-23 | — | — | CN | claimed |
| CN-101541331-A | Novel macrolides and ketolides with antimicrobial activity | WOCKHARDT RESEARCH CENTER (IN) | 2009-09-23 | — | — | CN | disclosed |
| EP-1082308-A1 | HETEROCYCLICALLY SUBSTITUTED AMIDES USED AS CALPAIN INHIBITORS | BASF AKTIENGESELLSCHAFT (DE) | 2001-03-14 | — | — | EP | disclosed |
| WO-1999054305-A1 | HETEROCYCLICALLY SUBSTITUTED AMIDES USED AS CALPAIN INHIBITORS | BASF AKTIENGESELLSCHAFT (DE) | 1999-10-28 | — | — | WO | disclosed |
| CN-1046529-A | Carbostyril derivative | OTSUKA PHARMA CO LTD (JP) | 1990-10-31 | — | — | CN | disclosed |