Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | HTR6 | P50406 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | GABRP | O00591 | 1/20 | 0.44 |
| ▸ | GABRD | O14764 | 1/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.44 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.44 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.44 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.44 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.44 |
| ▸ | GABRE | P78334 | 1/20 | 0.44 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.44 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.44 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3868019 | 0.80 | MAPT (0.65) | MAPTCYP3A4HTR6HSD17B10SMN1; SMN2 | |
| SCHEMBL9359189 | 0.75 | HSD17B10 (0.54) | HSD17B10GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL11495271 | 0.75 | CYP3A4 (0.61) | MAPTCYP3A4HTR6HSD17B10SMN1; SMN2 | |
| 2-Methyl Gramine SCHEMBL2519973 | 0.73 | MAPT (1.00) | MAPTCYP3A4HTR6HSD17B10SMN1; SMN2 | |
| SCHEMBL11495830 | 0.72 | HTR2A (0.71) | MAPTCYP3A4HTR6HTR2AHTR2C | |
| SCHEMBL1727453 | 0.71 | NPC1 (0.51) | MAPTHSD17B10SMN1; SMN2GABRPGABRD | |
| Hydrochloric Acid SCHEMBL7402385 | 0.70 | LTA4H (0.49) | MAPTHTR6GABRPGABRDGABRA1 | |
| SCHEMBL3233129 | 0.69 | CYP3A4 (0.67) | MAPTCYP3A4HTR6HSD17B10SMN1; SMN2 | |
| SCHEMBL9816424 | 0.69 | FOLH1 (0.66) | MAPTCYP3A4HTR6ALDH1A1HPGD | |
| SCHEMBL30833299 | 0.69 | ADRB2 (0.47) | MAPTCYP3A4HTR6GABRPGABRD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992014709-A2 | CALCIUM CHANNEL ANTAGONISTS AND METHODOLOGY FOR THEIR IDENTIFICATION | CAMBRIDGE NEUROSCIENCE, INC. (US) | 1992-09-03 | — | — | WO | disclosed |