Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 7/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | PRKCA | P17252 | 3/20 | 0.33 |
| ▸ | CTSL | P07711 | 3/20 | 0.32 |
| ▸ | CTSB | P07858 | 3/20 | 0.32 |
| ▸ | CTSH | P09668 | 2/20 | 0.32 |
| ▸ | CTSS | P25774 | 2/20 | 0.32 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.32 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.32 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL969953 | 0.82 | CTSK (0.36) | CTSKATMCTSLCTSBCTSH | |
| SCHEMBL970772 | 0.82 | CTSK (0.36) | CTSKATMCTSLCTSBCTSH | |
| SCHEMBL7364108 | 0.79 | CTSK (0.33) | CTSKATMCTSLCTSBCTSH | |
| SCHEMBL2443112 | 0.77 | MEN1 (0.35) | CTSKPRKCACTSLCTSB | |
| SCHEMBL7363475 | 0.76 | CTSS (0.30) | CTSS | |
| SCHEMBL7364034 | 0.76 | CTSS (0.30) | CTSS | |
| SCHEMBL7360069 | 0.74 | ATM (0.39) | CTSKATMCTSLCTSBCTSS | |
| SCHEMBL7319609 | 0.74 | — | — | |
| SCHEMBL7289613 | 0.70 | GRN (0.35) | CTSKPRKCACTSLCTSBCTSS | |
| SCHEMBL8827086 | 0.70 | GRN (0.35) | CTSKPRKCACTSLCTSBCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0270234-A2 | Renin inhibitors | PFIZER INC. (US) | 1988-06-08 | — | — | EP | disclosed |
| WO-1988003022-A1 | RELATIVELY LOW MOLECULAR WEIGHT POLYPEPTIDES AS RENIN INHIBITORS | PFIZER INC. (US) | 1988-05-05 | — | — | WO | disclosed |