SCHEMBL7363475

SCHEMBL7363475

C=C(C)CC1CC(C(CC2CCCCC2)N(C(=O)O)C(C)(C)C)OC1=O

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CTSS P25774 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7364108 0.87 CTSK (0.33) CTSS
SCHEMBL7364034 0.86 CTSS (0.30) CTSS
SCHEMBL7360069 0.82 ATM (0.39) CTSS
SCHEMBL7360310 0.76 CTSK (0.35) CTSS
SCHEMBL969953 0.75 CTSK (0.36) CTSS
SCHEMBL970772 0.75 CTSK (0.36) CTSS
SCHEMBL10425107 0.74 CTSS (0.41) CTSS
SCHEMBL9533345 0.74 CTSS (0.41) CTSS
SCHEMBL9750429 0.74 CTSS (0.41) CTSS
SCHEMBL7273551 0.66 CTSS (0.41) CTSS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0270234-A2 Renin inhibitors PFIZER INC. (US) 1988-06-08 EP disclosed
WO-1988003022-A1 RELATIVELY LOW MOLECULAR WEIGHT POLYPEPTIDES AS RENIN INHIBITORS PFIZER INC. (US) 1988-05-05 WO disclosed