Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7360194 | 0.97 | MAPT (0.43) | NPC1KDM4EMAPTPOLBRAB9A | |
| SCHEMBL7355377 | 0.95 | SMN1; SMN2 (0.44) | ALDH1A1KDM4EMAPTMAPK1TP53 | |
| Hydrochloric Acid SCHEMBL7360641 | 0.95 | PARP1 (0.42) | ALDH1A1NPC1KDM4EMAPTPOLB | |
| SCHEMBL7357135 | 0.95 | KDM4E (0.42) | ALDH1A1RECQLNPC1KDM4EMAPT | |
| SCHEMBL7351818 | 0.93 | ALDH1A1 (0.45) | ALDH1A1NPC1KDM4EMAPTPOLB | |
| SCHEMBL7360674 | 0.93 | CYP2C19 (0.42) | NPC1KDM4EMAPTRAB9ANOTUM | |
| SCHEMBL7356099 | 0.93 | MCHR1 (0.45) | SMN1; SMN2PARP1 | |
| SCHEMBL7354615 | 0.91 | NOTUM (0.44) | ALDH1A1NPC1KDM4EMAPTPOLB | |
| SCHEMBL7354626 | 0.90 | KDM4E (0.43) | NPC1KDM4EMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL7355443 | 0.90 | KDM4E (0.42) | KDM4EMAPTSMN1; SMN2HSD17B10PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995003298-A1 | BENZIMIDAZOLE DERIVATIVES USEFUL AS DOPAMINE RECEPTOR ANTAGONIST, 5-HT RECEPTOR AGONIST OR α1 RECEPTOR ANTAGONIST | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-02-02 | — | — | WO | disclosed |