Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.41 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7351996 | 0.97 | ALDH1A1 (0.42) | MAPTKDM4ESMN1; SMN2NPC1RAB9A | |
| SCHEMBL7357135 | 0.95 | KDM4E (0.42) | MAPTKDM4ESMN1; SMN2TSHRNPC1 | |
| Hydrochloric Acid SCHEMBL7360641 | 0.95 | PARP1 (0.42) | MAPTKDM4ETSHRNPC1RAB9A | |
| SCHEMBL7351818 | 0.93 | ALDH1A1 (0.45) | MAPTKDM4ESMN1; SMN2TSHRNPC1 | |
| SCHEMBL7356099 | 0.93 | MCHR1 (0.45) | SMN1; SMN2P2RY14LMNA | |
| SCHEMBL7355377 | 0.92 | SMN1; SMN2 (0.44) | MAPTKDM4ESMN1; SMN2KMT2AMEN1 | |
| SCHEMBL7360674 | 0.91 | CYP2C19 (0.42) | MAPTKDM4ESMN1; SMN2NPC1RAB9A | |
| SCHEMBL7354615 | 0.89 | NOTUM (0.44) | MAPTKDM4ESMN1; SMN2TSHRNPC1 | |
| SCHEMBL7354626 | 0.89 | KDM4E (0.43) | MAPTKDM4ESMN1; SMN2NPC1RAB9A | |
| SCHEMBL7355443 | 0.88 | KDM4E (0.42) | MAPTKDM4ESMN1; SMN2KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995003298-A1 | BENZIMIDAZOLE DERIVATIVES USEFUL AS DOPAMINE RECEPTOR ANTAGONIST, 5-HT RECEPTOR AGONIST OR α1 RECEPTOR ANTAGONIST | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-02-02 | — | — | WO | disclosed |