Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | RAD52 | P43351 | 1/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7351996 | 0.95 | ALDH1A1 (0.42) | SMN1; SMN2TP53KDM4EALDH1A1MAPK1 | |
| SCHEMBL7360194 | 0.92 | MAPT (0.43) | SMN1; SMN2TP53MEN1KMT2ALMNA | |
| Hydrochloric Acid SCHEMBL7360641 | 0.90 | PARP1 (0.42) | TP53MEN1KMT2AKDM4ERAD52 | |
| SCHEMBL7357135 | 0.90 | KDM4E (0.42) | SMN1; SMN2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL7360674 | 0.90 | CYP2C19 (0.42) | SMN1; SMN2LMNAKDM4EMAPT | |
| SCHEMBL7351818 | 0.89 | ALDH1A1 (0.45) | SMN1; SMN2KMT2ALMNAKDM4EALDH1A1 | |
| SCHEMBL7356099 | 0.88 | MCHR1 (0.45) | SMN1; SMN2HTTLMNAMCHR1 | |
| SCHEMBL7354615 | 0.88 | NOTUM (0.44) | SMN1; SMN2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL7354626 | 0.88 | KDM4E (0.43) | SMN1; SMN2MEN1KMT2ALMNAKDM4E | |
| SCHEMBL7355443 | 0.87 | KDM4E (0.42) | SMN1; SMN2KMT2ALMNAKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995003298-A1 | BENZIMIDAZOLE DERIVATIVES USEFUL AS DOPAMINE RECEPTOR ANTAGONIST, 5-HT RECEPTOR AGONIST OR α1 RECEPTOR ANTAGONIST | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-02-02 | — | — | WO | disclosed |