Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.58 |
| ▸ | IDO1 | P14902 | 3/20 | 0.49 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4075672 | 0.82 | LOXL2 (0.49) | LOXL2IDO1F2OPRK1 | |
| SCHEMBL7355775 | 0.81 | LOXL2 (0.59) | LOXL2AOC3HRH3 | |
| SCHEMBL653529 | 0.80 | LOXL2 (0.63) | LOXL2IDO1OPRK1AOC3HRH3 | |
| SCHEMBL30105384 | 0.78 | LOXL2 (0.60) | LOXL2IDO1F2OPRK1 | |
| SCHEMBL2592547 | 0.78 | LOXL2 (0.60) | LOXL2IDO1OPRK1AOC3HRH3 | |
| SCHEMBL5642064 | 0.78 | LOXL2 (0.60) | LOXL2IDO1OPRK1AOC3HRH3 | |
| SCHEMBL3193871 | 0.78 | LOXL2 (0.60) | LOXL2IDO1F2OPRK1 | |
| SCHEMBL7549813 | 0.77 | LOXL2 (0.59) | LOXL2AOC3HRH3 | |
| SCHEMBL4333117 | 0.77 | LOXL2 (0.59) | LOXL2IDO1OPRK1AOC3HRH3 | |
| SCHEMBL7374709 | 0.77 | LOXL2 (0.55) | LOXL2IDO1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0722321-A4 | SULFOXIMINE AND SULFODIIMINE MATRIX METALLOPROTEINASE INHIBITORS | UNIV FLORIDA STATE (US) | 1998-04-15 | — | — | EP | disclosed |
| EP-0722321-A1 | SULFOXIMINE AND SULFODIIMINE MATRIX METALLOPROTEINASE INHIBITORS | FLORIDA STATE UNIVERSITY (US) | 1996-07-24 | — | — | EP | disclosed |
| WO-1995009620-A1 | SULFOXIMINE AND SULFODIIMINE MATRIX METALLOPROTEINASE INHIBITORS | FLORIDA STATE UNIVERSITY (US) | 1995-04-13 | — | — | WO | disclosed |