Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ1 | P48048 | 3/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.52 |
| ▸ | RORC | P51449 | 1/20 | 0.45 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | PLG | P00747 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7362873 | 0.80 | RORC (0.44) | KCNJ1KCNH2RORCP2RX7PLG | |
| SCHEMBL2846720 | 0.77 | PKM (0.62) | RORCSIGMAR1CYP19A1PKM | |
| SCHEMBL23902730 | 0.76 | GLS (0.46) | PLGPLAUCYP19A1HTR7 | |
| SCHEMBL2479169 | 0.76 | HTR7 (0.47) | PLGPLAUCYP19A1HTR7 | |
| SCHEMBL2263041 | 0.76 | GLS (0.46) | PLGPLAUCYP19A1PKMHTR7 | |
| SCHEMBL30241520 | 0.76 | GLS (0.46) | PLGPLAUCYP19A1HTR7 | |
| SCHEMBL6637649 | 0.76 | KCNJ1 (0.53) | KCNJ1KCNH2CYP19A1PKM | |
| SCHEMBL9640859 | 0.76 | KCNH2 (0.68) | KCNJ1KCNH2SIGMAR1CYP19A1 | |
| SCHEMBL7357276 | 0.76 | KRAS (0.52) | RORCARPKM | |
| SCHEMBL10430002 | 0.75 | PLG (0.46) | PLGPLAUCYP19A1HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999028297-A1 | SUBSTITUTED INDOLES, HAVING A THROMBIN INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1999-06-10 | — | — | WO | disclosed |