Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.41 |
| ▸ | PRKCI | P41743 | 1/20 | 0.41 |
| ▸ | PLAU | P00749 | 2/20 | 0.40 |
| ▸ | PLG | P00747 | 1/20 | 0.40 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | DHFR | P00374 | 1/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 2/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | CDC7 | O00311 | 1/20 | 0.36 |
| ▸ | CDK4 | P11802 | 2/20 | 0.36 |
| ▸ | CCND1 | P24385 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7360923 | 0.80 | KCNJ1 (0.52) | RORCP2RX7CYP19A1PLAUPLG | |
| SCHEMBL17060376 | 0.74 | PRKCI (0.49) | RORCPRKCIPLAUHTR6CDK4 | |
| SCHEMBL5089820 | 0.73 | PRKCI (0.56) | PRKCIPLAUPLGHSD17B10CDK4 | |
| SCHEMBL30364718 | 0.73 | PLAU (0.54) | CYP19A1PLAUPLGHTR6 | |
| SCHEMBL14855116 | 0.73 | PLAU (0.54) | CYP19A1PLAUPLGHTR6 | |
| SCHEMBL6636265 | 0.73 | BRPF1 (0.40) | RORCPRKCIKCNJ1KCNH2TSHR | |
| SCHEMBL17242442 | 0.72 | P2RX7 (0.54) | RORCP2RX7CYP19A1PLAUPLG | |
| SCHEMBL9642642 | 0.72 | LOXL2 (0.54) | KCNJ1KCNH2TSHRHSD17B10 | |
| SCHEMBL7354891 | 0.72 | NTSR1 (0.52) | RORCTSHRHSD17B10 | |
| SCHEMBL6355917 | 0.71 | PRKCI (0.46) | CYP19A1PRKCIPLAUPLGHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999028297-A1 | SUBSTITUTED INDOLES, HAVING A THROMBIN INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1999-06-10 | — | — | WO | disclosed |