Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | DAGLA | Q9Y4D2 | 2/20 | 0.39 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7355527 | 0.87 | MEN1 (0.43) | KMT2AMEN1HPGDSMN1; SMN2TSHR | |
| SCHEMBL7511580 | 0.84 | LMNA (0.42) | KMT2AMEN1SMN1; SMN2PDE4APDE4B | |
| SCHEMBL7843449 | 0.82 | PDE4A (0.40) | KMT2AMEN1SMN1; SMN2PDE4APDE4B | |
| SCHEMBL7850685 | 0.81 | NOS3 (0.40) | DAGLAPOLBCYP2D6 | |
| SCHEMBL7352951 | 0.78 | SMN1; SMN2 (0.34) | SMN1; SMN2LMNACYP2C19 | |
| SCHEMBL7893458 | 0.78 | RIPK2 (0.46) | KMT2AMEN1SMN1; SMN2TSHRPDE4A | |
| SCHEMBL7893498 | 0.75 | PDE2A (0.42) | KMT2AMEN1SMN1; SMN2PDE4APDE4B | |
| SCHEMBL6996007 | 0.75 | PDE4A (0.41) | KMT2AMEN1PDE4APDE4BPDE4C | |
| SCHEMBL7510987 | 0.74 | LMNA (0.39) | KMT2AMEN1SMN1; SMN2PDE4APDE4B | |
| SCHEMBL6997649 | 0.73 | LMNA (0.38) | KMT2AMEN1SMN1; SMN2PDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6458796-B1 | METHOD OF TREATING CARDIOVASCULAR DISORDERS, THROMBOEMBOLIC DISORDERS AND ISCHAEMIAS, AND UROGENITAL SYSTEM DISORDERS, COMPRISING ADMINISTERING TO MAMMALS | BAYER AKTIENGESELLSCHAFT (DE) | 2002-10-01 | — | — | US | disclosed |