Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK2 | O43353 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7885859 | 0.87 | RIPK2 (0.43) | RIPK2FAAHPDE4APDE4BPDE4C | |
| SCHEMBL6996007 | 0.82 | PDE4A (0.41) | FAAHPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7381725 | 0.81 | PDE4A (0.39) | PDE4APDE4BPDE4CPDE4DGRIK1 | |
| SCHEMBL7378633 | 0.81 | TSHR (0.49) | PDE4APDE4BPDE4CPDE4DTSHR | |
| SCHEMBL7361207 | 0.78 | KMT2A (0.45) | FAAHPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6997571 | 0.77 | ALDH1A1 (0.38) | FAAHKMT2AMEN1TSHRALDH1A1 | |
| SCHEMBL27481625 | 0.76 | L3MBTL1 (0.34) | KMT2AMEN1TSHRLMNAL3MBTL1 | |
| SCHEMBL7893498 | 0.75 | PDE2A (0.42) | FAAHPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7511580 | 0.75 | LMNA (0.42) | PDE4APDE4BPDE4CPDE4DKMT2A | |
| SCHEMBL7843449 | 0.72 | PDE4A (0.40) | PDE4APDE4BPDE4CPDE4DKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1151155-C | 1, 5-dihydro-pyrazolo [3, 4-D ] -pyrimidone derivatives | — | 2004-05-26 | — | — | CN | disclosed |
| US-6174884-B1 | CARDIOVASCULAR DISORDERS; CEREBROVASCULAR DISEASES; VASCULAR SYSTEM DISORDERS, ESPECIALLY THE PERIPHERAL BLOOD VESSELS; UROGENITAL DISORDERS; HYPOTENSIVE AGENTS; ANTIARRYTHMIA AND -ISCHEMIC AGENTS; PHOSPHODIESTERASE ACTIVITY | BAYER AKTIENGESELLSCHAFT (DE) | 2001-01-16 | — | — | US | disclosed |
| CN-1255133-A | 1,5-dihydro-pyrazolo [3,4-D]-pyrimidinone derivatives | BAYER AG (DE) | 2000-05-31 | — | — | CN | disclosed |