Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7356719 | 0.90 | HPGD (0.44) | ALDH1A1KDM4EMEN1HPGDKMT2A | |
| SCHEMBL7359893 | 0.88 | KMT2A (0.43) | ALDH1A1HSD17B10KDM4EHPGDKMT2A | |
| SCHEMBL7358498 | 0.84 | SMN1; SMN2 (0.39) | HDAC1ALDH1A1HSD17B10KDM4EHPGD | |
| SCHEMBL7360074 | 0.81 | SIGMAR1 (0.42) | HDAC1HDAC6ALDH1A1HSD17B10KDM4E | |
| Hydrochloric Acid SCHEMBL7350285 | 0.80 | SIGMAR1 (0.41) | HDAC1HDAC6ALDH1A1HSD17B10KDM4E | |
| SCHEMBL7355990 | 0.80 | EGLN3 (0.40) | ALDH1A1KDM4ESMN1; SMN2TSHRHTT | |
| Hydrochloric Acid SCHEMBL7357414 | 0.78 | PRPS1 (0.38) | ALDH1A1KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7353986 | 0.75 | KDM4E (0.36) | HDAC1HDAC6ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL7355082 | 0.73 | EGLN1 (0.45) | ALDH1A1HSD17B10KDM4EMEN1HPGD | |
| SCHEMBL7358428 | 0.73 | EGLN1 (0.40) | ALDH1A1KDM4ENPSR1SMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995003298-A1 | BENZIMIDAZOLE DERIVATIVES USEFUL AS DOPAMINE RECEPTOR ANTAGONIST, 5-HT RECEPTOR AGONIST OR α1 RECEPTOR ANTAGONIST | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-02-02 | — | — | WO | disclosed |