Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7361803 | 0.84 | HDAC1 (0.46) | SMN1; SMN2ALDH1A1KDM4EHSD17B10GAA | |
| SCHEMBL7354368 | 0.82 | HTR1A (0.40) | SMN1; SMN2ALDH1A1KDM4EHSD17B10MAPK1 | |
| SCHEMBL7358428 | 0.77 | EGLN1 (0.40) | SMN1; SMN2ALDH1A1KDM4EEGLN1LMNA | |
| SCHEMBL7355082 | 0.77 | EGLN1 (0.45) | SMN1; SMN2ALDH1A1KDM4EHSD17B10GAA | |
| SCHEMBL7355990 | 0.77 | EGLN3 (0.40) | SMN1; SMN2ALDH1A1KDM4EEGLN1LMNA | |
| Hydrochloric Acid SCHEMBL7357414 | 0.76 | PRPS1 (0.38) | SMN1; SMN2ALDH1A1KDM4EEGLN1LMNA | |
| SCHEMBL7356719 | 0.76 | HPGD (0.44) | SMN1; SMN2ALDH1A1KDM4EGAAHPGD | |
| SCHEMBL7350014 | 0.74 | HPGD (0.54) | SMN1; SMN2ALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL7359893 | 0.74 | KMT2A (0.43) | ALDH1A1KDM4EHSD17B10GAAHPGD | |
| SCHEMBL7356668 | 0.73 | ALDH1A1 (0.48) | SMN1; SMN2ALDH1A1KDM4EHSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995003298-A1 | BENZIMIDAZOLE DERIVATIVES USEFUL AS DOPAMINE RECEPTOR ANTAGONIST, 5-HT RECEPTOR AGONIST OR α1 RECEPTOR ANTAGONIST | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-02-02 | — | — | WO | disclosed |