Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 8/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.43 |
| ▸ | PDE4A | P27815 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.42 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7370206 | 0.91 | SMN1; SMN2 (0.47) | SMN1; SMN2NPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL7363949 | 0.91 | TBXAS1 (0.46) | SMN1; SMN2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7369488 | 0.90 | HPGD (0.50) | SMN1; SMN2MEN1KMT2APDE4AALDH1A1 | |
| SCHEMBL7370566 | 0.85 | MEN1 (0.51) | SMN1; SMN2MEN1KMT2APDE4AALDH1A1 | |
| SCHEMBL7365377 | 0.83 | PDE4A (0.54) | MEN1KMT2APDE4AALDH1A1PDE4B | |
| SCHEMBL7366350 | 0.83 | PDE4A (0.64) | SMN1; SMN2PDE4AALDH1A1PDE4BPDE4C | |
| SCHEMBL7369334 | 0.82 | ALDH1A1 (0.48) | MEN1KMT2APDE4AALDH1A1PDE4B | |
| SCHEMBL7361314 | 0.82 | TBXAS1 (0.46) | SMN1; SMN2MEN1KMT2APDE4APDE4B | |
| SCHEMBL7360999 | 0.81 | HPGD (0.53) | SMN1; SMN2MEN1KMT2APDE4AALDH1A1 | |
| SCHEMBL7365898 | 0.81 | PDE4B (0.49) | SMN1; SMN2PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993007146-A1 | BENZO AND PYRIDO PYRIDAZINONE AND PYRIDAZINTHIONE COMPOUNDS WITH PDE IV INHIBITING ACTIVITY | SYNTEX (U.S.A.) INC. (US) | 1993-04-15 | — | — | WO | disclosed |