Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 6/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | PDE4A | P27815 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7360999 | 0.91 | HPGD (0.53) | HPGDKAT2BMEN1KMT2APOLB | |
| SCHEMBL7365898 | 0.91 | PDE4B (0.49) | HPGDKAT2BPDE4APDE4BPDE4C | |
| SCHEMBL7362436 | 0.90 | SMN1; SMN2 (0.47) | MEN1KMT2APOLBPDE4AALDH1A1 | |
| SCHEMBL7370566 | 0.86 | MEN1 (0.51) | MEN1KMT2APDE4AALDH1A1PDE4B | |
| SCHEMBL7361626 | 0.84 | ALDH1A1 (0.56) | HPGDMEN1KMT2APDE4AALDH1A1 | |
| SCHEMBL7369334 | 0.83 | ALDH1A1 (0.48) | HPGDKAT2BMEN1KMT2APDE4A | |
| SCHEMBL7364240 | 0.82 | PDE4A (0.66) | HPGDKAT2BPDE4AALDH1A1PDE4B | |
| SCHEMBL7370613 | 0.81 | HPGD (0.52) | HPGDKAT2BPDE4APDE4BPDE4C | |
| SCHEMBL7370206 | 0.81 | SMN1; SMN2 (0.47) | HPGDMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL7363949 | 0.81 | TBXAS1 (0.46) | HPGDPDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993007146-A1 | BENZO AND PYRIDO PYRIDAZINONE AND PYRIDAZINTHIONE COMPOUNDS WITH PDE IV INHIBITING ACTIVITY | SYNTEX (U.S.A.) INC. (US) | 1993-04-15 | — | — | WO | disclosed |