Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | YAP1 | P46937 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | STS | P08842 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8477292 | 1.00 | YAP1 (0.42) | YAP1TP53LMNAMAPTTHRB | |
| SCHEMBL8479980 | 0.93 | TP53 (0.42) | TP53LMNAGPR119P2RX7 | |
| Hydrochloric Acid SCHEMBL8473467 | 0.86 | ALDH1A1 (0.39) | TP53MAPTL3MBTL1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8473462 | 0.86 | ALDH1A1 (0.39) | TP53MAPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL7363095 | 0.80 | GPR119 (0.46) | GPR119 | |
| SCHEMBL7364915 | 0.79 | GPR119 (0.45) | LMNAMAPTGPR119SMN1; SMN2 | |
| SCHEMBL8474677 | 0.79 | TP53 (0.42) | TP53LMNAMAPTGPR119P2RX7 | |
| SCHEMBL8474670 | 0.79 | TP53 (0.42) | TP53LMNAMAPTGPR119P2RX7 | |
| Hydrochloric Acid SCHEMBL7359799 | 0.79 | RAB9A (0.39) | SMN1; SMN2 | |
| SCHEMBL7365804 | 0.77 | GPR119 (0.56) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5994356-A | ANTICOAGULANT | KARL THOMAE (DE) | 1999-11-30 | — | — | US | disclosed |
| EP-0892783-A1 | CARBOXYLIC ACID DERIVATIVES WITH AN AGGREGATION-INHIBITING ACTION | Dr. Karl Thomae GmbH (DE) | 1999-01-27 | — | — | EP | disclosed |
| WO-1997037975-A1 | CARBOXYLIC ACID DERIVATIVES WITH AN AGGREGATION-INHIBITING ACTION | DR. KARL THOMAE GMBH (DE) | 1997-10-16 | — | — | WO | disclosed |