Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 1/20 | 0.58 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.58 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.56 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.55 |
| ▸ | CTRB1 | P17538 | 3/20 | 0.55 |
| ▸ | CTSL | P07711 | 1/20 | 0.48 |
| ▸ | ECE1 | P42892 | 1/20 | 0.46 |
| ▸ | ACE | P12821 | 1/20 | 0.46 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.44 |
| ▸ | HPGDS | O60760 | 1/20 | 0.44 |
| ▸ | MEP1B | Q16820 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7363566 | 0.88 | PIN1 (0.59) | FOLH1PIN1CTRB1CTSLECE1 | |
| SCHEMBL7364842 | 0.82 | PIN1 (0.49) | MMEMMEL1FOLH1PIN1CTRB1 | |
| SCHEMBL7443024 | 0.80 | PIN1 (0.49) | MMEPIN1CTRB1 | |
| SCHEMBL7364836 | 0.77 | ROCK2 (0.51) | FOLH1PIN1CTRB1 | |
| SCHEMBL7365324 | 0.76 | MME (0.66) | MMEPIN1CTRB1ACE | |
| SCHEMBL7789884 | 0.76 | ROCK2 (0.57) | MMEMMEL1PIN1CTRB1CTSL | |
| SCHEMBL7376451 | 0.76 | ROCK2 (0.57) | MMEMMEL1PIN1CTRB1CTSL | |
| SCHEMBL10779933 | 0.76 | PIN1 (0.61) | MMEPIN1CTRB1CTSLECE1 | |
| SCHEMBL10779929 | 0.76 | PIN1 (0.61) | MMEPIN1CTRB1CTSLECE1 | |
| SCHEMBL7370588 | 0.74 | MME (0.59) | MMEACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0117429-B1 | PHOSPHOROUS CONTAINING COMPOUNDS AS INHIBITORS OF ENKEPHALINASES | SCHERING CORPORATION (US) | 1987-09-02 | — | — | EP | claimed |
| EP-0117429-A1 | Phosphorous containing compounds as inhibitors of enkephalinases | SCHERING CORPORATION (US) | 1984-09-05 | — | — | EP | claimed |
| EP-0117429-B1 | PHOSPHOROUS CONTAINING COMPOUNDS AS INHIBITORS OF ENKEPHALINASES | SCHERING CORPORATION (US) | 1987-09-02 | — | — | EP | disclosed |
| EP-0117429-A1 | Phosphorous containing compounds as inhibitors of enkephalinases | SCHERING CORPORATION (US) | 1984-09-05 | — | — | EP | disclosed |