Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 3/20 | 0.51 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.51 |
| ▸ | FPR2 | P25090 | 9/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.45 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.44 |
| ▸ | PPIA | P62937 | 1/20 | 0.44 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7363566 | 0.85 | PIN1 (0.59) | ROCK2ROCK1FOLH1PIN1CTRB1 | |
| SCHEMBL9588002 | 0.83 | CTRB1 (0.59) | ROCK2ROCK1FPR2CTRB1 | |
| SCHEMBL7368874 | 0.80 | FOLH1 (0.53) | FOLH1 | |
| SCHEMBL7362894 | 0.77 | MME (0.58) | FOLH1PIN1CTRB1 | |
| SCHEMBL7367157 | 0.76 | NAALAD2 (0.58) | FPR2FOLH1 | |
| SCHEMBL7367862 | 0.76 | MME (0.54) | PIN1CTRB1 | |
| SCHEMBL7367162 | 0.76 | NAALAD2 (0.58) | FPR2FOLH1 | |
| SCHEMBL7369997 | 0.75 | NPC1 (0.51) | — | |
| SCHEMBL7370001 | 0.75 | NPC1 (0.51) | — | |
| SCHEMBL7443024 | 0.75 | PIN1 (0.49) | PIN1CTRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0117429-B1 | PHOSPHOROUS CONTAINING COMPOUNDS AS INHIBITORS OF ENKEPHALINASES | SCHERING CORPORATION (US) | 1987-09-02 | — | — | EP | claimed |
| EP-0117429-A1 | Phosphorous containing compounds as inhibitors of enkephalinases | SCHERING CORPORATION (US) | 1984-09-05 | — | — | EP | claimed |
| EP-0117429-B1 | PHOSPHOROUS CONTAINING COMPOUNDS AS INHIBITORS OF ENKEPHALINASES | SCHERING CORPORATION (US) | 1987-09-02 | — | — | EP | disclosed |
| EP-0117429-A1 | Phosphorous containing compounds as inhibitors of enkephalinases | SCHERING CORPORATION (US) | 1984-09-05 | — | — | EP | disclosed |