Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 7/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 5/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.39 |
| ▸ | HTR3B | O95264 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7368781 | 0.80 | USP2 (0.39) | USP2CYP2D6CYP3A4CYP1A2CYP2C9 | |
| SCHEMBL4749593 | 0.79 | USP2 (0.47) | USP2CYP2D6CYP3A4CYP1A2CYP2C9 | |
| SCHEMBL4746204 | 0.75 | USP2 (0.44) | USP2CYP2D6CYP3A4CYP1A2CYP2C9 | |
| SCHEMBL4749321 | 0.75 | USP2 (0.44) | USP2CYP2D6CYP3A4CYP1A2CYP2C9 | |
| SCHEMBL22893604 | 0.70 | LMNA (0.43) | USP2CYP2D6CYP3A4CYP1A2CYP2C9 | |
| Hydrochloric Acid SCHEMBL20487165 | 0.69 | LMNA (0.44) | USP2CYP2D6CYP3A4CYP1A2CYP2C9 | |
| SCHEMBL7290614 | 0.68 | USP2 (0.45) | USP2CYP2D6CYP3A4CYP1A2CYP2C9 | |
| SCHEMBL28889619 | 0.68 | OPRM1 (0.47) | USP2CYP2D6CYP3A4CYP1A2CYP2C9 | |
| SCHEMBL6991226 | 0.67 | OPRM1 (0.50) | USP2CYP2D6CYP3A4CYP1A2CYP2C9 | |
| SCHEMBL23332765 | 0.65 | DPP4 (0.36) | USP2CYP2D6CYP3A4CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4032642-A | SEDATIVES, TRANQUILIZERS | A. H. ROBINS COMPANY, INCORPORATED (US) | 1977-06-28 | — | — | US | disclosed |
| US-3956296-A | ANTIINFLAMMATORY, SEDATIVES, TRANQUILIZERS | A. H. ROBINS COMPANY, INCORPORATED (US) | 1976-05-11 | — | — | US | disclosed |