Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 6/20 | 0.64 |
| ▸ | GSK3B | P49841 | 9/20 | 0.47 |
| ▸ | HTR7 | P34969 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | GNG2 | P59768 | 1/20 | 0.39 |
| ▸ | GNB1 | P62873 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30005666 | 0.82 | PKM (0.42) | KDM4ELMNATP53MAPTALOX15 | |
| SCHEMBL3711398 | 0.82 | PKM (0.42) | KDM4ELMNATP53MAPTALOX15 | |
| SCHEMBL10327311 | 0.80 | PTPN1 (1.00) | PTPN1GSK3BHTR7NPC1RAB9A | |
| SCHEMBL120278 | 0.80 | PTPN1 (1.00) | PTPN1GSK3BHTR7NPC1RAB9A | |
| Methylsulfanylmethane SCHEMBL28782222 | 0.77 | PTPN1 (0.84) | PTPN1GSK3BHTR7NPC1RAB9A | |
| SCHEMBL6180855 | 0.76 | PTPN1 (0.53) | PTPN1GSK3BRAB9AGNG2GNB1 | |
| SCHEMBL7363929 | 0.75 | F2R (0.47) | KDM4ELMNATP53MAPTALOX15 | |
| SCHEMBL8793197 | 0.75 | PTPN1 (0.88) | PTPN1GSK3BHTR7NPC1RAB9A | |
| SCHEMBL4342176 | 0.72 | PTPN1 (0.53) | PTPN1GSK3BGNG2GNB1MAPT | |
| SCHEMBL1121618 | 0.72 | RAB9A (0.46) | PTPN1GSK3BNPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1112269-A2 | HIV PROTEASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 2001-07-04 | — | — | EP | disclosed |
| WO-2000015634-A2 | HIV PROTEASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 2000-03-23 | — | — | WO | disclosed |