SCHEMBL1121618

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL27625170	0.83	GSK3B (0.46)	RAB9AMAPTSMN1; SMN2NPC1PTPN1
	SCHEMBL966965	0.83	SIGMAR1 (0.46)	RAB9AMAPTSMN1; SMN2NPC1PTPN1
	SCHEMBL909444	0.81	PKM (0.53)	RAB9AMAPTPKMSMN1; SMN2NPC1
	SCHEMBL29814973	0.81	PKM (0.53)	RAB9AMAPTPKMSMN1; SMN2NPC1
	SCHEMBL3097072	0.81	MEN1 (0.47)	MAPTKMT2AMEN1MAPK1CYP3A4
	SCHEMBL1121619	0.80	ALDH1A1 (0.52)	RAB9AMAPTSMN1; SMN2NPC1PTPN1
	SCHEMBL2936987	0.79	GSK3B (0.52)	RAB9AMAPTSMN1; SMN2NPC1PTPN1
	SCHEMBL157139	0.76	P2RX7 (0.45)	MAPTPKMMAPK1CYP3A4KDM4E
	SCHEMBL1345638	0.76	P2RX7 (0.45)	PKMP2RX7
	SCHEMBL1344059	0.76	P2RX7 (0.45)	RAB9AMAPTPKMSMN1; SMN2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.