Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 2/20 | 0.47 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 5/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30480694 | 0.88 | F2R (0.48) | F2RPKMMAOBMAOACES2 | |
| SCHEMBL120277 | 0.88 | F2R (0.48) | F2RPKMMAOBMAOACES2 | |
| SCHEMBL30005666 | 0.84 | PKM (0.42) | F2RPKMP2RX7MAOBMAPT | |
| SCHEMBL3711398 | 0.84 | PKM (0.42) | F2RPKMP2RX7MAOBMAPT | |
| SCHEMBL12304999 | 0.79 | CES2 (0.45) | HSD17B1PKMMAOBMAOACES2 | |
| SCHEMBL157139 | 0.76 | P2RX7 (0.45) | F2RPKMP2RX7MAOBCES2 | |
| SCHEMBL5952920 | 0.76 | F2R (0.48) | F2RPKMCES2CES1MAPT | |
| SCHEMBL7363932 | 0.75 | PTPN1 (0.64) | PKMMAPTKDM4ELMNATP53 | |
| SCHEMBL8204240 | 0.74 | MAPT (0.46) | HSD17B1PKMMAOBMAOAMAPT | |
| SCHEMBL21780538 | 0.73 | F2R (0.56) | F2RPKMCES2CES1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1112269-A2 | HIV PROTEASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 2001-07-04 | — | — | EP | disclosed |
| WO-2000015634-A2 | HIV PROTEASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 2000-03-23 | — | — | WO | disclosed |