Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.38 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7368849 | 0.85 | ALDH1A1 (0.39) | F2POLBTP53MAPTMEN1 | |
| SCHEMBL7403846 | 0.84 | LTA4H (0.38) | — | |
| SCHEMBL6433018 | 0.84 | CFTR (0.38) | LPAR1LPAR5MEN1KMT2A | |
| SCHEMBL7400241 | 0.80 | PLAU (0.56) | TP53MAPTTHRBRAB9A | |
| SCHEMBL7389837 | 0.76 | ALDH1A1 (0.35) | TP53MAPTNPC1RAB9A | |
| SCHEMBL7406871 | 0.75 | POLB (0.52) | POLBMAPTMEN1NPC1KMT2A | |
| SCHEMBL7502539 | 0.74 | PLAU (0.54) | TP53MAPTTHRBMEN1NPC1 | |
| SCHEMBL7403313 | 0.74 | GAA (0.48) | RAB9A | |
| SCHEMBL7399154 | 0.73 | MAPT (0.48) | POLBMAPTMEN1NPC1RAB9A | |
| SCHEMBL7505548 | 0.73 | PLAU (0.47) | TP53MAPTTHRBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1242120-A2 | COMBINATIONS OF GROWTH FACTORS AND I:UPA OR I:MMP FOR THE TREATMENT OF DAMAGED TISSUE | Pfizer Limited (GB) | 2002-09-25 | — | — | EP | disclosed |
| WO-2001049309-A2 | COMBINATIONS OF GROWTH FACTORS AND I: UPA OR I: MMP FOR THE TREATMENT OF DAMAGED TISSUE | PFIZER LIMITED (GB) | 2001-07-12 | — | — | WO | disclosed |