SCHEMBL6433018

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL6433655	0.84	ALDH1A1 (0.40)	KMT2AMEN1PLAUALDH1A1HTT
	SCHEMBL6434696	0.83	NR1D1 (0.43)	CTSSKMT2AMEN1L3MBTL1PLAU
	SCHEMBL6433131	0.79	PLAU (0.58)	CTSSL3MBTL1PLAUCTSLTRPM8
	SCHEMBL6434223	0.74	RXRA (0.32)	PLAUALDH1A1
	SCHEMBL6434389	0.74	PTPRC (0.49)	KMT2AMEN1L3MBTL1ALDH1A1MAPK1
	SCHEMBL6433083	0.73	PLAU (0.57)	KMT2AMEN1L3MBTL1PLAULMNA
	SCHEMBL6435282	0.72	ROCK2 (0.53)	KMT2AMEN1ALDH1A1NPSR1MAPK1
	SCHEMBL6433264	0.72	ROCK2 (0.44)	—
	SCHEMBL6435278	0.72	ROCK2 (0.53)	KMT2AMEN1ALDH1A1NPSR1MAPK1
	SCHEMBL6433766	0.72	PLAU (0.51)	CTSSPLAUCTSLLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.