Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | LAP3 | P28838 | 2/20 | 0.38 |
| ▸ | ANPEP | P15144 | 1/20 | 0.38 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.38 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.38 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.38 |
| ▸ | CTSD | P07339 | 3/20 | 0.38 |
| ▸ | CTSE | P14091 | 1/20 | 0.38 |
| ▸ | PGC | P20142 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7279585 | 0.95 | CA2 (0.43) | RENCA2BACE1LAP3ANPEP | |
| SCHEMBL7270308 | 0.82 | ALDH1A1 (0.42) | CTRB1 | |
| SCHEMBL7362341 | 0.81 | MAPK1 (0.56) | ANPEPRNPEPDNPEPCTRB1 | |
| SCHEMBL7361627 | 0.81 | CTSB (0.52) | — | |
| SCHEMBL7268475 | 0.78 | ANPEP (0.37) | RENCA2BACE1LAP3ANPEP | |
| SCHEMBL7298969 | 0.78 | NPC1 (0.51) | CA2BACE1LAP3ANPEPRNPEP | |
| SCHEMBL6445202 | 0.78 | NPC1 (0.51) | CA2BACE1LAP3ANPEPRNPEP | |
| SCHEMBL7332765 | 0.78 | NPC1 (0.51) | CA2BACE1LAP3ANPEPRNPEP | |
| SCHEMBL6444710 | 0.78 | NPC1 (0.51) | CA2BACE1LAP3ANPEPRNPEP | |
| SCHEMBL6445073 | 0.78 | NPC1 (0.51) | CA2BACE1LAP3ANPEPRNPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0415981-A4 | RETROVIRAL PROTEASE INHIBITORS | — | 1991-10-09 | — | — | EP | disclosed |
| EP-0415981-A1 | RETROVIRAL PROTEASE INHIBITORS | ABBOTT LABORATORIES (US) | 1991-03-13 | — | — | EP | disclosed |
| EP-0342541-A2 | Retroviral protease inhibitors | ABBOTT LABORATORIES (US) | 1989-11-23 | — | — | EP | disclosed |
| WO-1989010752-A1 | RETROVIRAL PROTEASE INHIBITORS | ABBOTT LABORATORIES (US) | 1989-11-16 | — | — | WO | disclosed |