Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 7/20 | 0.52 |
| ▸ | CAPN1 | P07384 | 4/20 | 0.42 |
| ▸ | CTSL | P07711 | 3/20 | 0.40 |
| ▸ | CTSH | P09668 | 2/20 | 0.40 |
| ▸ | CTSK | P43235 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7358377 | 0.87 | CTSB (0.39) | CTSBCTSL | |
| SCHEMBL7270308 | 0.84 | ALDH1A1 (0.42) | — | |
| SCHEMBL5689533 | 0.83 | CTSB (0.63) | CTSBCAPN1CTSLCTSHCTSK | |
| SCHEMBL7362341 | 0.83 | MAPK1 (0.56) | — | |
| SCHEMBL7279585 | 0.83 | CA2 (0.43) | — | |
| SCHEMBL7364429 | 0.81 | REN (0.42) | — | |
| SCHEMBL20204693 | 0.76 | CTSC (0.58) | CTSBCAPN1CTSL | |
| SCHEMBL20204691 | 0.76 | CTSC (0.58) | CTSBCAPN1CTSL | |
| SCHEMBL14623960 | 0.74 | CTSB (0.54) | CTSBCAPN1CTSL | |
| SCHEMBL2740206 | 0.74 | CTSB (0.54) | CTSBCAPN1CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0415981-A4 | RETROVIRAL PROTEASE INHIBITORS | — | 1991-10-09 | — | — | EP | disclosed |
| EP-0415981-A1 | RETROVIRAL PROTEASE INHIBITORS | ABBOTT LABORATORIES (US) | 1991-03-13 | — | — | EP | disclosed |
| EP-0342541-A2 | Retroviral protease inhibitors | ABBOTT LABORATORIES (US) | 1989-11-23 | — | — | EP | disclosed |
| WO-1989010752-A1 | RETROVIRAL PROTEASE INHIBITORS | ABBOTT LABORATORIES (US) | 1989-11-16 | — | — | WO | disclosed |