Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.53 |
| ▸ | AGXT | P21549 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.48 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.48 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.48 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | LDHA | P00338 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7720191 | 0.84 | HTT (0.53) | IDO1AGXTHTTALDH1A1NPC1 | |
| SCHEMBL99313 | 0.84 | FFAR1 (0.57) | IDO1AGXTHTTALDH1A1NPC1 | |
| SCHEMBL19002576 | 0.84 | HTT (0.53) | IDO1AGXTHTTALDH1A1NPC1 | |
| SCHEMBL4706402 | 0.82 | HTT (0.56) | IDO1AGXTHTTALDH1A1NPC1 | |
| SCHEMBL16542339 | 0.81 | RXRA (0.45) | IDO1HTTALDH1A1NPC1RAB9A | |
| SCHEMBL21664684 | 0.81 | RAB9A (0.54) | AGXTALDH1A1NPC1RAB9APOLB | |
| SCHEMBL4707348 | 0.81 | ALDH1A1 (0.57) | IDO1AGXTHTTALDH1A1NPC1 | |
| SCHEMBL16485634 | 0.81 | HTT (0.56) | IDO1AGXTHTTALDH1A1NPC1 | |
| SCHEMBL10072105 | 0.81 | HTT (0.50) | IDO1AGXTHTTALDH1A1NPC1 | |
| SCHEMBL24881284 | 0.80 | CALM1 (0.51) | POLBSMN1; SMN2F2RL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023220440-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2023-11-16 | — | — | WO | disclosed |
| US-5155228-A | FK-506 C10-C18 process intermediates | MERCK & CO., INC. (US) | 1992-10-13 | — | — | US | disclosed |
| US-4940797-A | Process for synthesis of FK-506 C10-C18 intermediates | MERCK & CO., INC. (US) | 1990-07-10 | — | — | US | disclosed |