Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 5/20 | 0.44 |
| ▸ | HPN | P05981 | 1/20 | 0.41 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 3/20 | 0.40 |
| ▸ | PLG | P00747 | 3/20 | 0.39 |
| ▸ | F12 | P00748 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.39 |
| ▸ | PROC | P04070 | 1/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7364282 | 0.92 | ALOX15 (0.41) | BACE1ITGB3ITGA2BALOX15HSD17B10 | |
| SCHEMBL7161019 | 0.91 | POLB (0.43) | F2PLGF12PLAUKLKB1 | |
| SCHEMBL7370705 | 0.90 | HSD17B10 (0.46) | HPNST14BACE1ALOX15HSD17B10 | |
| SCHEMBL7468966 | 0.87 | BDKRB1 (0.39) | F10HPNST14F2ITGB3 | |
| SCHEMBL7370604 | 0.86 | ITGB3 (0.46) | F10HPNST14ITGB3HSD17B10 | |
| SCHEMBL7370120 | 0.86 | HSD17B10 (0.41) | ITGB3ITGA2BALOX15HSD17B10 | |
| SCHEMBL7472561 | 0.85 | ITGB3 (0.41) | F10HPNST14ITGB3ITGA2B | |
| SCHEMBL7165857 | 0.83 | MMP2 (0.47) | ITGB3ITGA2BALOX15HSD17B10 | |
| SCHEMBL7367335 | 0.82 | GAA (0.40) | ALOX15HSD17B10 | |
| SCHEMBL7366599 | 0.82 | ITGB3 (0.41) | ITGB3ITGA2BALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0964856-B1 | BICYCLIC AMINO ACIDS | MERCK PATENT GMBH (DE) | 2002-10-09 | — | — | EP | disclosed |
| EP-0964856-A1 | BICYCLIC AMINO ACIDS | MERCK PATENT GmbH (DE) | 1999-12-22 | — | — | EP | disclosed |
| WO-1998035949-A1 | BICYCLIC AMINO ACIDS | MERCK PATENT GMBH (DE) | 1998-08-20 | — | — | WO | disclosed |