Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.45 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7370828 | 0.84 | LMNA (0.47) | ABCB1LMNAPOLBCYP2D6ADRB2 | |
| SCHEMBL11882587 | 0.78 | POLB (0.52) | ABCB1LMNAPOLBCYP2D6ADRB2 | |
| SCHEMBL11882590 | 0.75 | MAPK1 (0.53) | ABCB1LMNAPOLBCYP2D6ADRB2 | |
| SCHEMBL7336029 | 0.74 | POLB (0.47) | ABCB1LMNAPOLBCYP2D6ADRB2 | |
| SCHEMBL11792509 | 0.72 | HTR1A (0.53) | ABCB1CYP2D6ADRB2ADRB1ADRB3 | |
| SCHEMBL11882594 | 0.72 | MAPK1 (0.63) | LMNAPOLBCYP2D6MAPK1KDM4E | |
| SCHEMBL6017384 | 0.72 | TDP1 (0.55) | ABCB1LMNAADRB2ADRB1MAPK1 | |
| SCHEMBL15296872 | 0.71 | POLB (0.53) | ABCB1LMNAPOLBCYP2D6ADRB2 | |
| SCHEMBL258823 | 0.71 | HIF1A (0.75) | ABCB1LMNAPOLBCYP2D6ADRB2 | |
| SCHEMBL6931910 | 0.71 | MAPK1 (0.69) | LMNAPOLBCYP2D6ADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994002463-A1 | ANTIHYPERTENSIVE 1,4-DIHYDROPYRIDINE DERIVATIVES AND PROCESS FOR THEIR PREPARATION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-02-03 | — | — | WO | disclosed |