Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 12/20 | 0.46 |
| ▸ | TAS1R1 | Q7RTX1 | 12/20 | 0.46 |
| ▸ | MME | P08473 | 2/20 | 0.44 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7365213 | 1.00 | TAS1R3 (0.46) | TAS1R3TAS1R1MMEBIRC2POLB | |
| SCHEMBL7362044 | 0.87 | ALDH1A1 (0.51) | MMEFOLH1 | |
| SCHEMBL7362042 | 0.87 | ALDH1A1 (0.51) | MMEFOLH1 | |
| SCHEMBL19651554 | 0.84 | CTSK (0.42) | MME | |
| SCHEMBL19651560 | 0.83 | SMN1; SMN2 (0.44) | TAS1R3TAS1R1MMESMN1; SMN2 | |
| SCHEMBL11434953 | 0.81 | TAS1R3 (0.54) | TAS1R3TAS1R1BIRC2POLBFOLH1 | |
| SCHEMBL7751184 | 0.81 | TAS1R3 (0.54) | TAS1R3TAS1R1BIRC2POLBFOLH1 | |
| SCHEMBL19651549 | 0.81 | KDM4E (0.41) | MMESMN1; SMN2 | |
| SCHEMBL19651542 | 0.79 | LMNA (0.43) | SMN1; SMN2 | |
| SCHEMBL7279383 | 0.79 | FOLH1 (0.47) | TAS1R3TAS1R1MMEBIRC2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0415981-A4 | RETROVIRAL PROTEASE INHIBITORS | — | 1991-10-09 | — | — | EP | disclosed |
| EP-0415981-A1 | RETROVIRAL PROTEASE INHIBITORS | ABBOTT LABORATORIES (US) | 1991-03-13 | — | — | EP | disclosed |
| EP-0342541-A2 | Retroviral protease inhibitors | ABBOTT LABORATORIES (US) | 1989-11-23 | — | — | EP | disclosed |
| WO-1989010752-A1 | RETROVIRAL PROTEASE INHIBITORS | ABBOTT LABORATORIES (US) | 1989-11-16 | — | — | WO | disclosed |