Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE1 | P42892 | 5/20 | 0.57 |
| ▸ | MME | P08473 | 4/20 | 0.57 |
| ▸ | CTSB | P07858 | 4/20 | 0.53 |
| ▸ | CTSK | P43235 | 4/20 | 0.53 |
| ▸ | CTSL | P07711 | 5/20 | 0.51 |
| ▸ | CTSS | P25774 | 1/20 | 0.51 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | TACR1 | P25103 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7275434 | 0.88 | ECE1 (0.65) | ECE1MMECTSBCTSKCTSL | |
| SCHEMBL14438411 | 0.85 | ITGB3 (0.56) | ECE1MMECTSBCTSKCTSL | |
| SCHEMBL7444291 | 0.85 | ITGB3 (0.56) | ECE1MMECTSBCTSKCTSL | |
| SCHEMBL5561541 | 0.83 | ALDH1A1 (0.60) | CTSBCTSKCTSLCTSSTACR1 | |
| SCHEMBL5561531 | 0.83 | ALDH1A1 (0.60) | CTSBCTSKCTSLCTSSTACR1 | |
| SCHEMBL7355798 | 0.82 | CTSK (0.74) | CTSBCTSKCTSLCTSS | |
| SCHEMBL7355802 | 0.82 | CTSK (0.74) | CTSBCTSKCTSLCTSS | |
| SCHEMBL6150075 | 0.81 | ECE1 (0.48) | ECE1MMECTSBCTSKCTSL | |
| SCHEMBL6272667 | 0.80 | ECE1 (0.64) | ECE1MMECTSBCTSKCTSL | |
| SCHEMBL7378851 | 0.80 | ECE1 (0.64) | ECE1MMECTSBCTSKCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998025949-A1 | SUBSTITUTED 5-AMINO-1,3,4-THIADIAZOLE-2-THIONES | PROSCRIPT, INC. (US) | 1998-06-18 | — | — | WO | disclosed |
| EP-0845002-A2 | AMINO ACID AMIDES OF 5-AMINO-1,3,4-THIADIAZONES AND THEIR USE AS INHIBITORS FOR MATRIX METALLOPROTEINASES | PROSCRIPT, INC. (US) | 1998-06-03 | — | — | EP | disclosed |
| US-5677282-A | ENZYME INHIBITOR; OSTEOARTHRITIS AND RHEUMATIC DISORDERS | PROSCRIPT, INC. (US) | 1997-10-14 | — | — | US | disclosed |
| WO-1996040745-A2 | AMINO ACID AMIDES OF 5-AMINO-1,3,4-THIADIAZONES AND THEIR USE AS INHIBITORS FOR MATRIX METALLOPROTEINASES | PROSCRIPT, INC. (US) | 1996-12-19 | — | — | WO | disclosed |