Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 7/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.61 |
| ▸ | GAA | P10253 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL567927 | 0.80 | KDM4E (0.63) | CYP2D6CYP3A4CYP2C9CYP2C19GAA | |
| SCHEMBL567928 | 0.80 | KDM4E (0.63) | CYP2D6CYP3A4CYP2C9CYP2C19GAA | |
| SCHEMBL20502739 | 0.80 | KDM4E (0.63) | CYP2D6CYP3A4CYP2C9CYP2C19GAA | |
| SCHEMBL24094559 | 0.76 | CYP3A4 (0.61) | CYP2D6CYP3A4CYP2C9CYP2C19GAA | |
| SCHEMBL13744178 | 0.74 | CYP3A4 (0.59) | CYP2D6CYP3A4CYP2C9CYP2C19GAA | |
| SCHEMBL13118614 | 0.74 | LMNA (0.65) | CYP2D6CYP3A4CYP2C9CYP2C19GAA | |
| SCHEMBL7372315 | 0.74 | MMP1 (0.65) | CYP2D6CYP3A4CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL9234554 | 0.74 | KDM4E (0.56) | CYP2D6CYP3A4CYP2C9CYP2C19GAA | |
| SCHEMBL13398553 | 0.74 | GAA (0.67) | GAAKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL4503126 | 0.74 | KMT2A (0.62) | CYP2D6CYP3A4CYP2C9CYP2C19GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020099035-A1 | Method for preparing alpha-sulfonyl hydroxamic acid derivatives | WYETH HOLDINGS CORPORATION | 2002-07-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020099035-A1 | Method for preparing alpha-sulfonyl hydroxamic acid derivatives | MMP25, ADAMTS5, MMP9 | CYP2D6 951/4885CYP3A4 1112/4885CYP2C9 724/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.