Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 20/20 | 0.57 |
| ▸ | MMP2 | P08253 | 18/20 | 0.57 |
| ▸ | MMP1 | P03956 | 7/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7358585 | 0.87 | MMP13 (0.53) | MMP9MMP2MMP1 | |
| SCHEMBL8005755 | 0.83 | MMP9 (0.59) | MMP9MMP2MMP1 | |
| SCHEMBL10021363 | 0.78 | MMP9 (0.74) | MMP9MMP2MMP1 | |
| SCHEMBL8000461 | 0.77 | MMP9 (0.54) | MMP9MMP2MMP1 | |
| SCHEMBL7539094 | 0.76 | MMP2 (0.65) | MMP9MMP2MMP1 | |
| SCHEMBL7539103 | 0.76 | MMP2 (0.65) | MMP9MMP2MMP1 | |
| SCHEMBL8001929 | 0.76 | MMP9 (0.71) | MMP9MMP2MMP1 | |
| SCHEMBL7365907 | 0.75 | MMP2 (0.48) | MMP9MMP2MMP1 | |
| SCHEMBL8002778 | 0.74 | MMP9 (0.71) | MMP9MMP2MMP1 | |
| SCHEMBL7923030 | 0.73 | MMP9 (0.53) | MMP9MMP2MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235786-B1 | RHEUMATIC DISORDERS; BONE DISORDERS; ORAL DISEASES; ANTIULCER AGENTS; ANTITUMOR AGENTS | ABBOTT LABORATORIES | 2001-05-22 | — | — | US | claimed |
| WO-2000044712-A1 | N-HYDROXYFORMAMIDE DERIVATIVES AS INHIBITORS OF MATRIX METALLOPROTEINASES | ABBOTT LABORATORIES (US) | 2000-08-03 | — | — | WO | claimed |
| US-6235786-B1 | RHEUMATIC DISORDERS; BONE DISORDERS; ORAL DISEASES; ANTIULCER AGENTS; ANTITUMOR AGENTS | ABBOTT LABORATORIES | 2001-05-22 | — | — | US | disclosed |
| WO-2000044712-A1 | N-HYDROXYFORMAMIDE DERIVATIVES AS INHIBITORS OF MATRIX METALLOPROTEINASES | ABBOTT LABORATORIES (US) | 2000-08-03 | — | — | WO | disclosed |