Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.85 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.79 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.75 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.61 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | LTA4H | P09960 | 1/20 | 0.57 |
| ▸ | HRH1 | P35367 | 1/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11589061 | 0.88 | SIGMAR1 (1.00) | HRH3SIGMAR1SLC6A3MBTD1L3MBTL3 | |
| 1-Phenethylpiperidine SCHEMBL4054824 | 0.88 | SIGMAR1 (1.00) | HRH3SIGMAR1SLC6A3MBTD1L3MBTL3 | |
| SCHEMBL11922748 | 0.88 | SIGMAR1 (1.00) | HRH3SIGMAR1SLC6A3MBTD1L3MBTL3 | |
| 1-Phenethylpiperidine SCHEMBL917609 | 0.88 | SIGMAR1 (1.00) | HRH3SIGMAR1SLC6A3MBTD1L3MBTL3 | |
| SCHEMBL7925110 | 0.87 | LTA4H (0.75) | HRH3SIGMAR1SLC6A3LTA4HHRH1 | |
| 1-Phenethylpiperidine SCHEMBL11404041 | 0.86 | SIGMAR1 (0.96) | HRH3SIGMAR1SLC6A3MBTD1L3MBTL3 | |
| 1-Phenethylpiperidine SCHEMBL11507835 | 0.86 | SIGMAR1 (0.96) | HRH3SIGMAR1SLC6A3MBTD1L3MBTL3 | |
| 1-Phenethylpiperidine SCHEMBL31229056 | 0.86 | SIGMAR1 (0.96) | HRH3SIGMAR1SLC6A3MBTD1L3MBTL3 | |
| 1-Phenethylpiperidine SCHEMBL7524827 | 0.86 | SIGMAR1 (0.96) | HRH3SIGMAR1SLC6A3MBTD1L3MBTL3 | |
| 1-Phenethylpiperidine SCHEMBL27451069 | 0.86 | SIGMAR1 (0.96) | HRH3SIGMAR1SLC6A3MBTD1L3MBTL3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0714292-A4 | SIGMA RECEPTOR LIGANDS AND THE USE THEREOF | CAMBRIDGE NEUROSCIENCE INC (US) | 1996-10-09 | — | — | EP | claimed |
| EP-0714292-A1 | SIGMA RECEPTOR LIGANDS AND THE USE THEREOF | CAMBRIDGE NEUROSCIENCE, INC. (US) | 1996-06-05 | — | — | EP | claimed |
| WO-1995000131-A1 | SIGMA RECEPTOR LIGANDS AND THE USE THEREOF | CAMBRIDGE NEUROSCIENCE, INCORPORATED (US) | 1995-01-05 | — | — | WO | claimed |