Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.45 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HMOX1 | P09601 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7372181 | 0.77 | ALOX5 (0.51) | ALOX5L3MBTL1 | |
| SCHEMBL7369227 | 0.70 | QPCT (0.63) | CYP19A1CYP11B1CYP11B2MAPTHMOX1 | |
| SCHEMBL7366435 | 0.68 | MBTPS1 (0.47) | ALOX5 | |
| SCHEMBL11706076 | 0.68 | CYP17A1 (0.67) | CYP19A1CYP11B1CYP11B2CYP26A1CYP3A4 | |
| SCHEMBL9556461 | 0.67 | HRH4 (0.42) | CYP19A1CYP11B1CYP11B2CYP26A1 | |
| SCHEMBL2170633 | 0.67 | ALOX5 (0.67) | ALOX5LTA4H | |
| SCHEMBL7761599 | 0.66 | NR4A1 (0.62) | ALOX5 | |
| SCHEMBL6398854 | 0.66 | EGLN3 (0.40) | CYP19A1 | |
| SCHEMBL11099357 | 0.66 | LTA4H (0.56) | ALOX5L3MBTL1LTA4H | |
| SCHEMBL4435910 | 0.66 | ALOX5 (0.58) | ALOX5L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998054123-A1 | SUBSTITUTED PEPTIDYLAMINE CALCIUM CHANNEL BLOCKERS | WARNER-LAMBERT COMPANY (US) | 1998-12-03 | — | — | WO | claimed |
| WO-1998054123-A1 | SUBSTITUTED PEPTIDYLAMINE CALCIUM CHANNEL BLOCKERS | WARNER-LAMBERT COMPANY (US) | 1998-12-03 | — | — | WO | disclosed |