Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 11/20 | 0.57 |
| ▸ | MMP1 | P03956 | 11/20 | 0.56 |
| ▸ | MMP2 | P08253 | 7/20 | 0.56 |
| ▸ | MMP8 | P22894 | 6/20 | 0.52 |
| ▸ | MMP9 | P14780 | 5/20 | 0.52 |
| ▸ | MME | P08473 | 1/20 | 0.50 |
| ▸ | ANPEP | P15144 | 1/20 | 0.50 |
| ▸ | GLS | O94925 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7363698 | 1.00 | MMP3 (0.57) | MMP3MMP1MMP2MMP8MMP9 | |
| SCHEMBL7362031 | 0.92 | CTSK (0.49) | MMP3MMP1MMP2GLS | |
| SCHEMBL7362025 | 0.92 | CTSK (0.49) | MMP3MMP1MMP2GLS | |
| SCHEMBL6964283 | 0.89 | MMP3 (0.65) | MMP3MMP1MMP2MMP8MMP9 | |
| SCHEMBL6964276 | 0.89 | MMP3 (0.65) | MMP3MMP1MMP2MMP8MMP9 | |
| SCHEMBL7357861 | 0.87 | MMP3 (0.62) | MMP3MMP1MMP2MMP8MMP9 | |
| SCHEMBL7357865 | 0.87 | MMP3 (0.62) | MMP3MMP1MMP2MMP8MMP9 | |
| SCHEMBL7357677 | 0.86 | MMP1 (0.68) | MMP3MMP1MMP2MMP8MMP9 | |
| SCHEMBL7357689 | 0.86 | MMP1 (0.68) | MMP3MMP1MMP2MMP8MMP9 | |
| SCHEMBL6958535 | 0.85 | MMP3 (0.57) | MMP3MMP1MMP2GLS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998025949-A1 | SUBSTITUTED 5-AMINO-1,3,4-THIADIAZOLE-2-THIONES | PROSCRIPT, INC. (US) | 1998-06-18 | — | — | WO | disclosed |
| EP-0845002-A2 | AMINO ACID AMIDES OF 5-AMINO-1,3,4-THIADIAZONES AND THEIR USE AS INHIBITORS FOR MATRIX METALLOPROTEINASES | PROSCRIPT, INC. (US) | 1998-06-03 | — | — | EP | disclosed |
| WO-1996040745-A2 | AMINO ACID AMIDES OF 5-AMINO-1,3,4-THIADIAZONES AND THEIR USE AS INHIBITORS FOR MATRIX METALLOPROTEINASES | PROSCRIPT, INC. (US) | 1996-12-19 | — | — | WO | disclosed |