SCHEMBL7924872

SCHEMBL7924872

COC(=O)C[C@H]1C(=O)N(CC(=O)OC(=O)C(F)(F)F)CCN1C(=O)C(C)NC(=O)c1ccc(C2CCNCC2)cc1

nearest known ligand 0.40

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ITGB3 P05106 10/20 0.40
ITGA2B P08514 10/20 0.40
ITGA2 P17301 2/20 0.37
ALDH1A1 P00352 1/20 0.36
MAPT P10636 1/20 0.36
LMNA P02545 1/20 0.36
KMT2A Q03164 1/20 0.36
CCR1 P32246 6/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL7924867 0.90 ITGB3 (0.48) ITGB3ITGA2BITGA2LMNACCR1
Trifluoroacetic Acid SCHEMBL7366990 0.90 ITGB3 (0.48) ITGB3ITGA2BITGA2LMNACCR1
SCHEMBL7366992 0.85 ALDH1A1 (0.34) ITGB3ITGA2BITGA2ALDH1A1MAPT
SCHEMBL7931569 0.84 ITGB3 (0.42) ITGB3ITGA2BALDH1A1MAPTLMNA
SCHEMBL7924876 0.76 ITGB3 (0.49) ITGB3ITGA2BITGA2KMT2A
SCHEMBL7924865 0.76 ITGB3 (0.49) ITGB3ITGA2BITGA2KMT2A
SCHEMBL7924873 0.76 ITGB3 (0.49) ITGB3ITGA2BITGA2KMT2A
Trifluoroacetic Acid SCHEMBL7931567 0.74 ITGB3 (0.49) ITGB3ITGA2B
Trifluoroacetic Acid SCHEMBL7370443 0.74 ITGB3 (0.49) ITGB3ITGA2B
SCHEMBL7374179 0.72 ITGB3 (0.40) ITGB3ITGA2BKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6242600-B1 ANTIISCHEMIC AGENTS, ANTICOAGULANTS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2001-06-05 US disclosed