Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 3/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.30 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7364293 | 0.87 | DPP8 (0.41) | DPP4DPP8DPP7CYP3A4CYP2D6 | |
| SCHEMBL7372151 | 0.85 | DPP4 (0.40) | DPP4DPP8DPP7CYP3A4CYP2D6 | |
| SCHEMBL7369431 | 0.75 | L3MBTL1 (0.34) | DPP4DPP8DPP7CYP3A4CYP2D6 | |
| SCHEMBL7367999 | 0.74 | ALDH1A1 (0.39) | ITGB3ITGA2BALDH1A1GAA | |
| SCHEMBL7438854 | 0.72 | DPP8 (0.42) | DPP4DPP8DPP7CYP3A4CYP2D6 | |
| Trifluoroacetic Acid SCHEMBL7924834 | 0.71 | DPP8 (0.47) | DPP4DPP8DPP7CYP3A4CYP2D6 | |
| Trifluoroacetic Acid SCHEMBL7364289 | 0.71 | DPP8 (0.47) | DPP4DPP8DPP7CYP3A4CYP2D6 | |
| Trifluoroacetic Acid SCHEMBL7365694 | 0.71 | DPP8 (0.47) | DPP4DPP8DPP7CYP3A4CYP2D6 | |
| SCHEMBL7937529 | 0.67 | RORC (0.35) | ITGB3ITGA2BALDH1A1 | |
| SCHEMBL7372688 | 0.67 | CASP1 (0.36) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0970071-A1 | 2-PEPERAZINONE-1-ACETIC ACID DERIVATIVES AND THEIR USE | Takeda Chemical Industries, Ltd. (JP) | 2000-01-12 | — | — | EP | disclosed |
| WO-1998039324-A1 | 2-PEPERAZINONE-1-ACETIC ACID DERIVATIVES AND THEIR USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-11 | — | — | WO | disclosed |