Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 7/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7367242 | 0.87 | ITGB3 (0.42) | RORCCASP1ITGB3ITGA2B | |
| SCHEMBL7931599 | 0.87 | ITGB3 (0.42) | RORCCASP1ITGB3ITGA2B | |
| SCHEMBL7931603 | 0.87 | ITGB3 (0.42) | RORCCASP1ITGB3ITGA2B | |
| SCHEMBL7372688 | 0.86 | CASP1 (0.36) | CASP1ITGB3ITGA2B | |
| SCHEMBL7937532 | 0.78 | ITGB3 (0.34) | RORCCASP1ITGB3ITGA2BMAPK1 | |
| SCHEMBL7937544 | 0.78 | CASP1 (0.34) | CASP1ITGB3ITGA2B | |
| SCHEMBL7367244 | 0.77 | RORC (0.36) | RORCLMNA | |
| Hydrochloric Acid SCHEMBL7364672 | 0.76 | ITGB3 (0.44) | ITGB3ITGA2B | |
| SCHEMBL7372151 | 0.75 | DPP4 (0.40) | ITGB3ITGA2BALDH1A1HSD17B10 | |
| SCHEMBL7371269 | 0.74 | ITGB3 (0.39) | CASP1ITGB3ITGA2BTMEM97SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242600-B1 | ANTIISCHEMIC AGENTS, ANTICOAGULANTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-06-05 | — | — | US | disclosed |