Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.56 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.54 |
| ▸ | LNPEP | Q9UIQ6 | 3/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | LTA4H | P09960 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | LAP3 | P28838 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | ADAM33 | Q9BZ11 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7373437 | 1.00 | DPP7 (0.56) | DPP7HRH3LNPEPPKMLTA4H | |
| SCHEMBL7365786 | 0.88 | NPC1 (0.55) | DPP7LNPEPLTA4HRAB9ALAP3 | |
| SCHEMBL7696633 | 0.83 | DPP7 (0.60) | DPP7HRH3LNPEPLTA4HRAB9A | |
| SCHEMBL7365328 | 0.83 | NPC1 (0.56) | DPP7HRH3LTA4HRAB9ANPC1 | |
| SCHEMBL7341842 | 0.83 | NPC1 (0.56) | DPP7HRH3LTA4HRAB9ANPC1 | |
| SCHEMBL7366398 | 0.82 | DPP7 (0.71) | DPP7HRH3LTA4HRAB9ALAP3 | |
| SCHEMBL7371156 | 0.81 | HTT (0.57) | DPP7HRH3LNPEPLTA4HRAB9A | |
| SCHEMBL27386689 | 0.80 | LTA4H (0.65) | LNPEPLTA4HLAP3 | |
| SCHEMBL7281929 | 0.79 | MMP9 (0.63) | LNPEPLTA4HLAP3 | |
| Hydrochloric Acid SCHEMBL10350044 | 0.78 | MMP9 (0.62) | LNPEPLTA4HLAP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6117841-A | USED TO TREAT STROKE, CEREBRAL ISCHEMIA, PAIN, HEAD TRAUMA OR EPILEPSY | WARNER-LAMBERT COMPANY (US) | 2000-09-12 | — | — | US | disclosed |
| WO-1998054123-A1 | SUBSTITUTED PEPTIDYLAMINE CALCIUM CHANNEL BLOCKERS | WARNER-LAMBERT COMPANY (US) | 1998-12-03 | — | — | WO | disclosed |