Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | LNPEP | Q9UIQ6 | 3/20 | 0.51 |
| ▸ | LTA4H | P09960 | 8/20 | 0.48 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.48 |
| ▸ | DPP4 | P27487 | 1/20 | 0.48 |
| ▸ | FAP | Q12884 | 1/20 | 0.48 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.48 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.48 |
| ▸ | LAP3 | P28838 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 2/20 | 0.47 |
| ▸ | PPARA | Q07869 | 2/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7373437 | 0.88 | DPP7 (0.56) | NPC1RAB9ALNPEPLTA4HDPP7 | |
| SCHEMBL7367648 | 0.88 | DPP7 (0.56) | NPC1RAB9ALNPEPLTA4HDPP7 | |
| SCHEMBL7371920 | 0.84 | NPC1 (0.58) | NPC1RAB9ALTA4HDPP7DPP4 | |
| SCHEMBL7375300 | 0.83 | NPC1 (0.52) | NPC1RAB9ALTA4HMMP1ADAM17 | |
| SCHEMBL27386689 | 0.78 | LTA4H (0.65) | LNPEPLTA4HLAP3PPARGPPARA | |
| SCHEMBL7364841 | 0.77 | SLC6A5 (0.61) | NPC1RAB9APOLB | |
| SCHEMBL7368538 | 0.77 | SLC6A5 (0.61) | NPC1RAB9APOLB | |
| SCHEMBL7281929 | 0.77 | MMP9 (0.63) | LNPEPLTA4HLAP3PPARG | |
| SCHEMBL7314098 | 0.76 | LNPEP (0.57) | LNPEPLTA4HLAP3PPARGPPARA | |
| SCHEMBL7696633 | 0.76 | DPP7 (0.60) | NPC1RAB9ALNPEPLTA4HDPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6117841-A | USED TO TREAT STROKE, CEREBRAL ISCHEMIA, PAIN, HEAD TRAUMA OR EPILEPSY | WARNER-LAMBERT COMPANY (US) | 2000-09-12 | — | — | US | claimed |
| US-6117841-A | USED TO TREAT STROKE, CEREBRAL ISCHEMIA, PAIN, HEAD TRAUMA OR EPILEPSY | WARNER-LAMBERT COMPANY (US) | 2000-09-12 | — | — | US | disclosed |
| WO-1998054123-A1 | SUBSTITUTED PEPTIDYLAMINE CALCIUM CHANNEL BLOCKERS | WARNER-LAMBERT COMPANY (US) | 1998-12-03 | — | — | WO | disclosed |