SCHEMBL169145

SCHEMBL169145

CC(C)Cn1cnc2c(=O)n(C)c(=O)[nH]c21

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
APAF1 O14727 1/20 0.40
CASP6 P55212 1/20 0.40
ALDH1A1 P00352 4/20 0.39
LMNA P02545 1/20 0.39
CYP3A4 P08684 1/20 0.39
MAPT P10636 1/20 0.39
TSHR P16473 1/20 0.39
BLM P54132 1/20 0.39
PMP22 Q01453 1/20 0.39
HPGD P15428 3/20 0.39
TLR7 Q9NYK1 1/20 0.39
PDE2A O00408 1/20 0.38
PDE1A P54750 1/20 0.38
PDE1B Q01064 1/20 0.38
PDE1C Q14123 1/20 0.38
HSD17B10 Q99714 2/20 0.38
CYP2C9 P11712 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7367989 0.87 ALDH1A1 (0.46) KDM4EMEN1KMT2AAPAF1CASP6
SCHEMBL2948723 0.79 GAA (0.53) KDM4EMEN1KMT2AALDH1A1TSHR
SCHEMBL9199287 0.79 LMNA (0.40) KDM4EMEN1KMT2AAPAF1CASP6
SCHEMBL652922 0.77 MAPK1 (0.39) KDM4EMEN1KMT2AALDH1A1LMNA
SCHEMBL9299928 0.77 LMNA (0.60) ALDH1A1LMNACYP3A4MAPTTSHR
SCHEMBL515776 0.76 ALDH1A1 (0.54) KDM4EMEN1KMT2AAPAF1CASP6
SCHEMBL60160 0.76 PNP (0.47) KDM4EMEN1KMT2AALDH1A1LMNA
SCHEMBL10432471 0.75 HSD17B10 (0.49) KDM4EMEN1KMT2AALDH1A1LMNA
SCHEMBL8359284 0.73 PDE1A (0.39) ALDH1A1LMNACYP3A4MAPTTSHR
SCHEMBL29015257 0.72 KDM4E (0.34) KDM4EMEN1KMT2AALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 511 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111759828-A Composition and application thereof in treating and/or preventing dementia 许悦郎 2020-10-13 CN claimed
US-20160274087-A1 SCREENING ASSAY FOR AGENTS THAT INFLUENCE BETA CELL NUMBER AND/OR PHENOTYPE VRIJE UNIVERSITEIT BRUSSEL (BE) 2016-09-22 US claimed
EP-3066468-A1 SCREENING ASSAY FOR AGENTS THAT INFLUENCE BETA CELL NUMBER AND/OR PHENOTYPE Vrije Universiteit Brussel (BE) 2016-09-14 EP claimed
WO-2015067744-A1 SCREENING ASSAY FOR AGENTS THAT INFLUENCE BETA CELL NUMBER AND/OR PHENOTYPE VRIJE UNIVERSITEIT BRUSSEL (BE) 2015-05-14 WO claimed
US-4337254-A ANTICOAGULANTS COMPRISING A PROSTACYCLIN AND A PHOSPHODIESTERASE INHIBITOR; PREVENTING LOWERING OF BLOOD PRESSURE BURROUGHS WELLCOME CO. (US) 1982-06-29 US claimed
US-12605361-B2 Carboxylated psilocybin derivatives and methods of using Enveric Biosciences Canada Inc. (CA) 2026-04-21 US disclosed
US-20260103442-A1 AMINATED PSILOCYBIN DERIVATIVES AND METHODS OF USING ENVERIC BIOSCIENCES CANADA INC (CA) 2026-04-16 US disclosed
US-12514882-B2 Faecalibacterium prausnitzii strain EB-FPDK11 and use thereof ENTEROBIOME INC. (KR) 2026-01-06 US disclosed
US-20250352512-A2 C4-SUBSTITUTED TRYPTAMINE DERIVATIVES AND METHODS OF USING ENVERIC BIOSCIENCES CANADA INC (CA) 2025-11-20 US disclosed
US-20250352513-A2 SALTS OF C4-CARBOXYLIC ACID- AND C4-CARBONOTHIOATE-SUBSTITUTED TRYPTAMINE DERIVATIVES AND METHODS OF USING ENVERIC BIOSCIENCES CANADA INC (CA) 2025-11-20 US disclosed
EP-4630067-A1 3D FAT TISSUE STRUCTURE, PRODUCED USING LIGHT-BASED STRUCTURING CURING, FOR USE AS A BREAST IMPLANT Cellbricks GmbH (DE) 2025-10-15 EP disclosed
US-20250304643-A1 PEPTIDE DUAL AGONISTS OF GIPR AND GLP2R BAINAN BIOTECH APS (DK) 2025-10-02 US disclosed
EP-0567562-B1 METHODS FOR DETECTING GLUCAGON ANTAGONISTS ZYMOGENETICS INC (US) 1996-03-13 EP disclosed
EP-0658170-A1 GLUCAGON ANTAGONISTS AND METHODS FOR DETECTING GLUCAGON ANTAGONISTS ZYMOGENETICS, INC. (US) 1995-06-21 EP disclosed
US-5408037-A Antidiabetic agents; genetic engineering ZYMOGENETICS, INC. (US) 1995-04-18 US disclosed
WO-1994014427-A2 USE OF SKYRIN AND ANALOGUES FOR THE TREATMENT OF DIABETES MELLITUS AND PROCESS FOR THEIR PREPARATION ZYMOGENETICS, INC. (US) 1994-07-07 WO disclosed
US-5310759-A Methods of protecting and preserving connective and support tissues BOCKMAN RICHARD S 1994-05-10 US disclosed
WO-1994005699-A1 GLUCAGON ANTAGONISTS AND METHODS FOR DETECTING GLUCAGON ANTAGONISTS ZYMOGENETICS, INC. (US) 1994-03-17 WO disclosed
EP-0567562-A1 METHODS FOR DETECTING GLUCAGON ANTAGONISTS. ZYMOGENETICS INC (US) 1993-11-03 EP disclosed
WO-1992012998-A1 METHODS FOR DETECTING GLUCAGON ANTAGONISTS ZYMOGENETICS, INC. (US) 1992-08-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250352512-A2 C4-SUBSTITUTED TRYPTAMINE DERIVATIVES AND METHODS OF USING HTR4, HTR2C, HTR3C KDM4E 707/4885MEN1 635/4885KMT2A 1177/4885
US-20260103442-A1 AMINATED PSILOCYBIN DERIVATIVES AND METHODS OF USING HTR2C, CNR2, HTR2B KDM4E 958/4885MEN1 4004/4885KMT2A 1298/4885
US-20250352513-A2 SALTS OF C4-CARBOXYLIC ACID- AND C4-CARBONOTHIOATE-SUBSTITUTED TRYPTAMINE DERIVATIVES AND METHODS OF USING SLC6A4, HTR4, SLC6A3 KDM4E 2668/4885MEN1 933/4885KMT2A 1482/4885
US-12605361-B2 Carboxylated psilocybin derivatives and methods of using CNR2, HTR2B, HTR2C KDM4E 358/4885MEN1 4314/4885KMT2A 1138/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.