SCHEMBL30849698

SCHEMBL30849698

COc1ccc(OC)c(CNC(C)=O)c1

nearest known ligand 0.73

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MTNR1A P48039 2/20 0.69
MTNR1B P49286 2/20 0.69
HSD17B10 Q99714 1/20 0.59
HTT P42858 2/20 0.55
ALDH1A1 P00352 1/20 0.55
GAA P10253 1/20 0.55
PKM P14618 1/20 0.55
HPGD P15428 1/20 0.55
HIF1A Q16665 1/20 0.54
CNR1 P21554 1/20 0.54
CNR2 P34972 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10141758 0.87 APLNR (0.65) MTNR1AMTNR1BHTTALDH1A1GAA
SCHEMBL13647189 0.84 HSD17B10 (0.56) MTNR1AMTNR1BHSD17B10HTTALDH1A1
SCHEMBL18183442 0.84 MTNR1B (0.84) MTNR1AMTNR1B
SCHEMBL8460016 0.84 MTNR1A (0.50) MTNR1AMTNR1BHSD17B10HTTALDH1A1
SCHEMBL19625146 0.84 MTNR1A (0.54) MTNR1AMTNR1B
SCHEMBL20738484 0.84 MTNR1A (0.53) MTNR1AMTNR1BALDH1A1GAAHPGD
SCHEMBL13647314 0.83 SHMT2 (0.57) MTNR1AMTNR1BHSD17B10HTTALDH1A1
SCHEMBL4856579 0.83 MTNR1A (0.49) MTNR1AMTNR1BHTTALDH1A1GAA
SCHEMBL20738591 0.83 SETDB1 (0.53) MTNR1AMTNR1BALDH1A1
SCHEMBL8644052 0.83 ALDH1A1 (0.61) ALDH1A1GAAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260061083-A1 POSITRON EMISSION TOMOGRAPHY RADIOTRACER FOR DISEASES ASSOCIATED WITH TRANSLOCATOR PROTEIN OVEREXPRESSION, TRANSLOCATOR PROTEIN-TARGETING LIGAND FOR FLUORESCENCE IMAGING-GUIDED SURGERY AND PHOTODYNAMIC THERAPY, AND PRODUCTION METHODS THEREFOR SEOUL NATIONAL UNIVERSITY R&DB FOUNDATGON (KR) 2026-03-05 US disclosed
US-12491271-B2 Positron emission tomography radiotracer for diseases associated with translocator protein overexpression, translocator protein-targeting ligand for fluorescence imaging-guided surgery and photodynamic therapy, and production methods therefor SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (KR) 2025-12-09 US disclosed
US-20240156997-A1 POSITRON EMISSION TOMOGRAPHY RADIOTRACER FOR DISEASES ASSOCIATED WITH TRANSLOCATOR PROTEIN OVEREXPRESSION, TRANSLOCATOR PROTEIN-TARGETING LIGAND FOR FLUORESCENCE IMAGING-GUIDED SURGERY AND PHOTODYNAMIC THERAPY, AND PRODUCTION METHODS THEREFOR SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (KR) 2024-05-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260061083-A1 POSITRON EMISSION TOMOGRAPHY RADIOTRACER FOR DISEASES ASSOCIATED WITH TRANSLOCATOR PROTEIN OVEREXPRESSION, TRANSLOCATOR PROTEIN-TARGETING LIGAND FOR FLUORESCENCE IMAGING-GUIDED SURGERY AND PHOTODYNAMIC THERAPY, AND PRODUCTION METHODS THEREFOR TSPO, FABP7, SLC46A1 MTNR1A 1125/4885MTNR1B 1005/4885HSD17B10 2232/4885
US-12491271-B2 Positron emission tomography radiotracer for diseases associated with translocator protein overexpression, translocator protein-targeting ligand for fluorescence imaging-guided surgery and photodynamic therapy, and production methods therefor TSPO, FABP7, SLC46A1 MTNR1A 347/4885MTNR1B 528/4885HSD17B10 1891/4885
US-20240156997-A1 POSITRON EMISSION TOMOGRAPHY RADIOTRACER FOR DISEASES ASSOCIATED WITH TRANSLOCATOR PROTEIN OVEREXPRESSION, TRANSLOCATOR PROTEIN-TARGETING LIGAND FOR FLUORESCENCE IMAGING-GUIDED SURGERY AND PHOTODYNAMIC THERAPY, AND PRODUCTION METHODS THEREFOR TSPO, FABP7, SLC46A1 MTNR1A 347/4885MTNR1B 528/4885HSD17B10 1891/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.